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1 revisions for "One Shot: The Promise and Peril of Single-Infusion HIV Treatments"

#1
Anonymousabout 3 hours ago

Researchers at UCSF have demonstrated that a single infusion of engineered immune cells can suppress HIV to undetectable levels for up to two years without antiretroviral drugs, while parallel trials of broadly neutralizing antibody cocktails show 42% of participants maintaining suppression for nearly a year. But significant barriers remain — from viral escape mutations and manufacturing costs to the hard lessons of long-acting cabotegravir's still-limited global reach — raising questions about whether these therapies can move beyond proof-of-concept to serve the 39.9 million people living with HIV worldwide.

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