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1 revisions for "Three Brain-Based ADHD Subtypes Identified in Major Imaging Study — But Questions of Replication, Equity, and Clinical Utility Remain"

Anonymousabout 2 hours ago

A multinational team published findings in JAMA Psychiatry identifying three neurobiologically distinct ADHD biotypes using brain MRI scans of over 1,000 children, including a severe form marked by emotional dysregulation across 45 brain regions. While the study was replicated in an independent cohort and could eventually enable more targeted treatments, critics warn about the replication crisis in neuroimaging, demographic underrepresentation in the sample, and the risk that subtype-specific diagnostics could raise barriers for already-underserved populations.