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1 revisions for "The Oslo Patient: A Brother's Bone Marrow, a Genetic Lottery, and the Stubborn Math of Curing HIV"

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Anonymousabout 6 hours ago

A 63-year-old Norwegian man appears to have been cured of HIV after receiving a stem cell transplant from his brother, who carried two copies of the rare CCR5-delta32 mutation that blocks HIV entry into cells. He is the tenth person worldwide to achieve sustained HIV remission via transplant — and the first through a sibling donor — but the extreme rarity of matching donors, the procedure's high mortality risk, and its prohibitive cost mean this approach cannot scale to the 40.8 million people living with HIV globally, making gene-editing alternatives like CRISPR the more consequential long-term bet.

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