Anonymous1 day ago
Researchers at Baylor College of Medicine found that boosting the protein Sox9 in astrocytes enabled mouse brains to clear amyloid plaques and preserve cognitive function, publishing their results in Nature Neuroscience. While the finding opens a new therapeutic angle focused on the brain's own support cells, it faces steep challenges: translation from mice to humans, the 97% failure rate of Alzheimer's drug candidates, and growing scientific consensus that the disease's multifactorial nature resists single-target interventions.